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Propylene Glycol USP Kosher – Safety Data Sheet (SDS)

Last Updated: January 13, 2023  Propylene Glycol USP Kosher (CAS 57-55-6) is a clear, odorless liquid widely used in pharmaceuticals, food, cosmetics, and industrial applications. This Safety Data Sheet (SDS) provides essential safety, handling, and regulatory information.

 

Link to SDS PDF


Quick Facts

  • Chemical Name: 1,2-Propanediol

  • CAS Number: 57-55-6

  • Supplier: Interstate Chemical Company, Hermitage, PA

  • Classification: Not hazardous under GHS

  • NFPA Ratings: Health (1), Flammability (1), Reactivity (0)


Hazards & Safety

  • GHS Classification: Not classified as hazardous

  • Labeling: No labeling required

  • Health Risks: Generally safe; may cause minor irritation in sensitive individuals

  • California Prop 65: Not listed


First Aid Measures

  • Inhalation: Move to fresh air; rest.

  • Skin Contact: Wash with mild soap and water.

  • Eye Contact: Rinse thoroughly with water; seek care if irritation persists.

  • Ingestion: Rinse mouth, do not induce vomiting, seek medical help.


Fire & Explosion Data

  • Flash Point: ~210 °F

  • Flammability: Slight hazard – must be preheated before ignition

  • Extinguishing Media: Foam, dry powder, CO₂, water spray

  • Decomposition: Carbon monoxide, carbon dioxide


Handling & Storage

  • Store in original container, cool, dry, ventilated area

  • Keep away from strong acids/bases, sunlight, and heat sources

  • Wash hands after handling


Exposure & PPE

  • No exposure limits established

  • Recommended PPE: Gloves, safety glasses


Physical & Chemical Properties

  • Appearance: Clear, colorless, odorless liquid

  • pH: 7–8

  • Boiling Point: ~370 °F

  • Melting Point: -60 °C

  • Density: 1.036 g/cm³ (8.64 lb/gal)

  • Viscosity: 20 mm²/s at 68 °F


Toxicology & Ecology

  • Toxicity: Low (oral LD50 rat = 20,000 mg/kg)

  • Biodegradability: Readily biodegradable

  • Aquatic Toxicity: Very low (LC50 fish = 51,600 mg/L)

  • Bioaccumulation: Not expected (Log Pow: -1.41 to -0.3)


Transport & Disposal

  • Transport: Not regulated by DOT, IATA, IMDG, TDG

  • Disposal: Follow local/national regulations; avoid environmental release