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Pesticide Remediation (Myclobutanil) Process Guide

This guide explains how to remediate myclobutanil and similar pesticide contaminants using a heptane dilution, pH-adjusted saline washes, T-41 bleaching clay, and a MagSil-PR chromatography column. It includes PPE, solvent ratios, media quantities, and step-by-step instructions for performing the full remediation workflow.

Link to Pesticide Remediation (Myclo) Instructions

Quick Facts

  • Process Name: Pesticide Remediation (Myclobutanil)
  • Category: SOP / Purification
  • Primary Sorbents: MagSil-PR, T-41
  • Primary Solvents: Heptane, Isopropanol, pH-adjusted saline
  • Skill Level: Advanced technician

Main Stages:

  1. Heptane dilution
  2. Acidic/alkaline/neutral saline washing
  3. T-41 bleaching
  4. MagSil-PR column remediation
  5. Solvent recovery
  6. Final short-path distillation

Safety & PPE

PPE Required:

  • Splash goggles
  • Lab coat
  • Gloves

Safety Notes:

  • SDS sheets are available for all chemicals used.
  • All remediation work must occur in a properly ventilated, hydrocarbon-safe environment.
  • Ensure no ignition sources are present near heptane or isopropanol.

Preparation & Solvent Ratios

Solvent & Media Concentrations
  • Full-strength materials are required:
    • Heptane
    • 99% USP Isopropyl Alcohol
    • MagSil-PR
    • T-41
Key Ratios

Step

Ratio

Distillate dilution

2 parts heptane : 1 part distillate

MagSil-PR preparation

1 part heptane : 1 part MagSil-PR

MagSil loading ratio

2 parts MagSil-PR : 1 part distillate

T-41 slurry (label instructions)

1 part isopropanol : 1 part MagSil-PR
  • Heptane and isopropanol are both used to flush the column later in the process.
  • Where this process occurs: Distillation of crude oil occurs in the short path still.

Step-by-Step Procedure

STEP 1 — Dilute Distillate in Heptane
  • Dissolve first-pass distillate in heptane at a 2:1 ratio (heptane : distillate).
  • Add the heptane/distillate solution to the reactor.

STEP 2 — Prepare Saline Solutions
  • Prepare 60 parts saline, using 1–5% salt in distilled water.
  • Divide the saline into three equal volumes:
    • One pH 4 (citric acid adjusted)
    • One pH 8 (sodium bicarbonate adjusted)
    • One neutral

STEP 3 — Perform Saline Washes
  • Run the washes in the following order:
    • Add pH 4 saline → mix in reactor for 10 minutes → drain.
    • Add pH 8 saline → mix for 10 minutes → drain.
    • Add neutral saline → mix for 10 minutes → drain.
  • These washes help remove pH-sensitive pesticide contaminants.

STEP 4 — Add T-41 Bleaching Clay
  • Add T-41 directly to the reactor solution per label instructions.
  • Mix according to manufacturer guidelines.

STEP 5 — Wet-Load MagSil-PR Column
  • Wet-load MagSil-PR in the chromatography column.
  • Drain the reactor solution into the top of the MagSil-PR column.
  • Collect all fractions together.
  • MagSil-PR acts as the primary remediation media for myclobutanil.

STEP 6 — Flush the Column
  • Before the column runs dry:
    • Flush with a volume of clean heptane.
    • Swap to a clean collection vessel.
    • Flush with a volume of clean isopropanol.
  • This ensures complete elution of cannabinoids and removes retained solvents.

STEP 7 — Recover Solvent & Redistill
  • Rotovap the heptane solution (see Solvent Recovery SOP).
  • Perform a second-pass short-path distillation to finalize purification.
  • This step removes residual pesticide traces and cleans up the terpene/cannabinoid profile.

T-41 Bleaching Method (Alternate/Additional Step)

For bleaching prior to chromatography:

  1. Heat oil to 90°C.
  2. Add 3–5% T-41.
  3. Mix for 20–30 minutes.
  4. Cool to 40–45°C.
  5. Add carrier solvent (ethanol or heptane).
  6. Filter through vacuum or pressure filtration.

Contact & Support

For chromatography equipment, media selection, or remediation system design:

📞 734-855-4890
 📧 support@usalabequipment.com