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Isopropyl Alcohol 99% – Safety Data Sheet (SDS)

Last Updated: July 14, 2020  Isopropyl Alcohol 99% (2-propanol) is a highly flammable solvent supplied by Interstate Chemical Company, Inc. It is classified as a Flammable Liquid (Category 2) and may cause drowsiness or dizziness (STOT SE Category 3).

Link to Safety Data Sheet (PDF)


Quick Facts

  • Product Name: Isopropyl Alcohol 99% (2-propanol)
  • CAS Number: 67-63-0
  • Product Code: 23400
  • Type: Solvent
  • Supplier: Interstate Chemical Company, Inc., 2797 Freedland Road, Hermitage, PA 16148, USA | 800-422-2436 | herm-eh&s@interstatechemical.com | www.interstatechemical.com
  • Emergency Phone: CHEMTREC +1-800-424-9300 (24-hour)
  • GHS Classification: Flammable Liquid – Category 2; STOT (Single Exposure) – Category 3
  • Signal Word: Danger
  • NFPA Ratings: Health (1), Flammability (3), Reactivity (0)

Hazards & Safety

  • Hazard Statements:
    • H225: Highly flammable liquid and vapor.
    • H336: May cause drowsiness or dizziness.
  • Precautionary Statements (selected):
    • Keep away from heat, hot surfaces, sparks, open flames; no smoking.
    • Keep container tightly closed; ground/bond container and receiving equipment.
    • Use explosion-proof electrical/ventilation; only non-sparking tools; take measures against static discharge.
    • Avoid breathing mist/vapors; use only outdoors or in well-ventilated areas.
    • Wear protective gloves/clothing/eye/face protection.
    • Store locked up in a well-ventilated place; keep cool.
    • Dispose of contents/container according to regulations.
  • California Prop 65: No listed substances.

First Aid Measures

  • Inhalation: Move to fresh air and rest; seek medical attention if unwell.
  • Skin Contact: Remove affected clothing; wash skin with mild soap and water, then rinse.
  • Eye Contact: Rinse immediately with plenty of water; obtain medical attention if pain/blinking/redness persists.
  • Ingestion: Rinse mouth; do not induce vomiting; seek emergency medical attention.
  • Note to Physicians: Treat symptomatically.

Fire & Explosion Data

  • Suitable Extinguishing Media: Foam, dry powder, carbon dioxide, water spray, sand.
  • Unsuitable Media: Do not use a heavy water stream.
  • Special Hazards: Vapors may form explosive mixtures and travel to ignition sources.
  • Firefighting Instructions: Cool exposed containers with water spray/fog; prevent runoff from entering drains.
  • Protective Gear: SCBA and full protective equipment.

Handling & Storage

  • Provide good ventilation to prevent vapor formation; wash hands after handling.
  • Store only in original container, tightly closed, in a cool, well-ventilated place; keep away from ignition sources and sunlight.
  • Incompatible with strong acids/bases.

Exposure & PPE

  • Exposure Limits (Isopropyl Alcohol, CAS 67-63-0):
    • ACGIH: TWA 200 ppm; STEL 400 ppm (Eye & URT irritant; CNS impair)
  • OSHA PEL: TWA 400 ppm (980 mg/m³)
  • Eyes/Face: Chemical goggles or safety glasses.
  • Hands: Protective gloves.
  • Respiratory: Wear appropriate mask/NIOSH-approved respirator if ventilation is inadequate.
  • General Hygiene: Do not eat, drink, or smoke during use.

Physical & Chemical Properties

  • Appearance: Clear, colorless liquid | Odor: Characteristic
  • Boiling Point: 82 °C (1013 hPa)
  • Flash Point: 12 °C
  • Auto-Ignition Temperature: 399 °C
  • Specific Gravity/Density: ~0.785 g/mL (785 kg/m³)
  • Partition Coefficient (log Pow): 0.05 (25 °C)

Stability & Reactivity

  • Chemical stability: Not established (handle under recommended conditions).
  • Avoid: Direct sunlight; extreme temperatures; ignition sources.
  • Incompatible Materials: Strong acids, strong bases.
  • Hazardous Decomposition: Fumes; CO, CO₂.
  • Hazardous polymerization: Not established/expected.

Toxicology & Ecology

  • Acute Toxicity (dermal, rabbit) LD₅₀: 12,870 mg/kg
  • Inhalation ATE (vapors/dust/mist): 73 mg/L/4h
  • IARC: 2-propanol – Group 3 (not classifiable).
  • STOT – Single Exposure: May cause drowsiness or dizziness.
  • Aquatic Toxicity (selected):
    • Fish (96 h): LC₅₀ ≈ 9640 mg/L (Pimephales promelas)
    • Daphnia (48 h): EC₅₀ ≈ 13299 mg/L
  • Persistence/Degradability: Readily biodegradable in water/soil (for 2-propanol).
  • Bioaccumulation: Low potential (log Kow < 4).

Transport & Disposal

  • DOT: UN1219, Isopropanol, Class 3, PG II; ERG 129
  • IMDG: UN1219, ISOPROPANOL (ISOPROPYL ALCOHOL), Class 3, PG II (12 °C c.c.)
  • IATA: UN1219, Isopropanol, Class 3, PG II
  • Disposal: Dispose per local/regional/national/international regulations; avoid release to environment.

Regulatory Status

  • TSCA: Listed
  • SARA 313: Subject to reporting (2-propanol)
  • US State RTK: NJ/PA RTK lists (2-propanol)
  • California Prop 65: None
  • NFPA: Health (1), Flammability (3), Reactivity (0); Personal Protection (HMIS): D