Isopropyl Alcohol 99% – Safety Data Sheet (SDS)
Last Updated: July 14, 2020 Isopropyl Alcohol 99% (2-propanol) is a highly flammable solvent supplied by Interstate Chemical Company, Inc. It is classified as a Flammable Liquid (Category 2) and may cause drowsiness or dizziness (STOT SE Category 3).
Link to Safety Data Sheet (PDF)
Quick Facts
- Product Name: Isopropyl Alcohol 99% (2-propanol)
- CAS Number: 67-63-0
- Product Code: 23400
- Type: Solvent
- Supplier: Interstate Chemical Company, Inc., 2797 Freedland Road, Hermitage, PA 16148, USA | 800-422-2436 | herm-eh&s@interstatechemical.com | www.interstatechemical.com
- Emergency Phone: CHEMTREC +1-800-424-9300 (24-hour)
- GHS Classification: Flammable Liquid – Category 2; STOT (Single Exposure) – Category 3
- Signal Word: Danger
- NFPA Ratings: Health (1), Flammability (3), Reactivity (0)
Hazards & Safety
- Hazard Statements:
- H225: Highly flammable liquid and vapor.
- H336: May cause drowsiness or dizziness.
- Precautionary Statements (selected):
- Keep away from heat, hot surfaces, sparks, open flames; no smoking.
- Keep container tightly closed; ground/bond container and receiving equipment.
- Use explosion-proof electrical/ventilation; only non-sparking tools; take measures against static discharge.
- Avoid breathing mist/vapors; use only outdoors or in well-ventilated areas.
- Wear protective gloves/clothing/eye/face protection.
- Store locked up in a well-ventilated place; keep cool.
- Dispose of contents/container according to regulations.
- California Prop 65: No listed substances.
First Aid Measures
- Inhalation: Move to fresh air and rest; seek medical attention if unwell.
- Skin Contact: Remove affected clothing; wash skin with mild soap and water, then rinse.
- Eye Contact: Rinse immediately with plenty of water; obtain medical attention if pain/blinking/redness persists.
- Ingestion: Rinse mouth; do not induce vomiting; seek emergency medical attention.
- Note to Physicians: Treat symptomatically.
Fire & Explosion Data
- Suitable Extinguishing Media: Foam, dry powder, carbon dioxide, water spray, sand.
- Unsuitable Media: Do not use a heavy water stream.
- Special Hazards: Vapors may form explosive mixtures and travel to ignition sources.
- Firefighting Instructions: Cool exposed containers with water spray/fog; prevent runoff from entering drains.
- Protective Gear: SCBA and full protective equipment.
Handling & Storage
- Provide good ventilation to prevent vapor formation; wash hands after handling.
- Store only in original container, tightly closed, in a cool, well-ventilated place; keep away from ignition sources and sunlight.
- Incompatible with strong acids/bases.
Exposure & PPE
- Exposure Limits (Isopropyl Alcohol, CAS 67-63-0):
- ACGIH: TWA 200 ppm; STEL 400 ppm (Eye & URT irritant; CNS impair)
- OSHA PEL: TWA 400 ppm (980 mg/m³)
- Eyes/Face: Chemical goggles or safety glasses.
- Hands: Protective gloves.
- Respiratory: Wear appropriate mask/NIOSH-approved respirator if ventilation is inadequate.
- General Hygiene: Do not eat, drink, or smoke during use.
Physical & Chemical Properties
- Appearance: Clear, colorless liquid | Odor: Characteristic
- Boiling Point: 82 °C (1013 hPa)
- Flash Point: 12 °C
- Auto-Ignition Temperature: 399 °C
- Specific Gravity/Density: ~0.785 g/mL (785 kg/m³)
- Partition Coefficient (log Pow): 0.05 (25 °C)
Stability & Reactivity
- Chemical stability: Not established (handle under recommended conditions).
- Avoid: Direct sunlight; extreme temperatures; ignition sources.
- Incompatible Materials: Strong acids, strong bases.
- Hazardous Decomposition: Fumes; CO, CO₂.
- Hazardous polymerization: Not established/expected.
Toxicology & Ecology
- Acute Toxicity (dermal, rabbit) LD₅₀: 12,870 mg/kg
- Inhalation ATE (vapors/dust/mist): 73 mg/L/4h
- IARC: 2-propanol – Group 3 (not classifiable).
- STOT – Single Exposure: May cause drowsiness or dizziness.
- Aquatic Toxicity (selected):
- Fish (96 h): LC₅₀ ≈ 9640 mg/L (Pimephales promelas)
- Daphnia (48 h): EC₅₀ ≈ 13299 mg/L
- Persistence/Degradability: Readily biodegradable in water/soil (for 2-propanol).
- Bioaccumulation: Low potential (log Kow < 4).
Transport & Disposal
- DOT: UN1219, Isopropanol, Class 3, PG II; ERG 129
- IMDG: UN1219, ISOPROPANOL (ISOPROPYL ALCOHOL), Class 3, PG II (12 °C c.c.)
- IATA: UN1219, Isopropanol, Class 3, PG II
- Disposal: Dispose per local/regional/national/international regulations; avoid release to environment.
Regulatory Status
- TSCA: Listed
- SARA 313: Subject to reporting (2-propanol)
- US State RTK: NJ/PA RTK lists (2-propanol)
- California Prop 65: None
- NFPA: Health (1), Flammability (3), Reactivity (0); Personal Protection (HMIS): D