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Acetone – Safety Data Sheet (SDS)

Acetone (propanone, CAS 67-64-1) is a highly flammable solvent used in cleaning, coatings, and cosmetics.  SDS issued by Carbon Chemistry Ltd., Watkins, CO.

Link to Safety Data Sheet (PDF)


Quick Facts

  • Product Name: Acetone, chemically pure

  • Synonyms: Propanone

  • CAS Number: 67-64-1

  • Supplier: Carbon Chemistry Ltd. (CHEMTREC CCN832309, +1-800-424-9300)

  • GHS Classification: Flammable Liquid Cat. 2; Eye Irritation Cat. 2; STOT SE Cat. 3 (drowsiness/dizziness)

  • Signal Word / Pictograms: Danger / GHS02, GHS07


Hazards & Safety

  • Hazard Statements: H225 Highly flammable liquid and vapor; H319 Causes serious eye irritation; H336 May cause drowsiness or dizziness.

  • Prevention: Keep away from heat/sparks/open flames; keep container tightly closed; ground/bond; use explosion-proof equipment and non-sparking tools; avoid breathing vapors; use only with adequate ventilation; wear protective gloves/eye protection.

  • Response: IF ON SKIN (or hair): remove contaminated clothing, rinse skin/shower. IF IN EYES: rinse cautiously with water, remove contacts, continue rinsing. IF INHALED: move to fresh air. If symptoms persist, get medical attention. Store in a cool, well-ventilated place. Dispose per regulations.


First Aid Measures

  • Eyes: Rinse with water for ≥15 minutes; get medical attention if irritation persists.

  • Skin: Wash with soap and water; launder contaminated clothing before reuse.

  • Inhalation: Remove to fresh air; support breathing if needed.

  • Ingestion: Do not induce vomiting; contact physician/poison control.

  • Notes: Treat symptomatically; consider target-organ CNS effects.


Fire & Explosion Data

  • Flash Point: −4 °F (−20 °C)

  • Extinguishing Media: Alcohol-resistant foam, dry chemical, CO₂, dry sand; do not use water jet.

  • Special Hazards: Vapors may form explosive mixtures with air; static ignition possible.

  • Firefighting: Full PPE and SCBA; cool containers with water spray; prevent runoff to drains.


Handling & Storage

  • Use polyethylene/lined steel/stainless systems; protect containers from damage.

  • Ground and bond all transfer equipment; use non-sparking tools and explosion-proof ventilation.

  • Store tightly closed, cool, dry, isolated, and well-ventilated; keep away from ignition sources and incompatibles.


Exposure & PPE

  • Exposure Limits: ACGIH TWA 250 ppm; OSHA PEL 1000 ppm (2400 mg/m³).

  • Controls: Provide local exhaust; ensure eyewash/safety shower access.

  • PPE: Safety glasses; suitable gloves; protective clothing as needed; respiratory protection if exposure may exceed limits.


Physical & Chemical Properties

  • State/Appearance/Odor: Colorless liquid; fruity/pungent odor

  • pH: ~7

  • Boiling Point: 132.8 °F (55 °C)

  • Flash Point: −4 °F (−20 °C)

  • Viscosity: 0.32 cP (20 °C)

  • Water Solubility: Miscible

  • Specific Gravity: 0.803 @ 20 °C


Stability & Reactivity

  • Stable under recommended storage.

  • Hazardous Reactions: Vapors may form explosive mixtures with air.

  • Avoid: Heat, flames, sparks.

  • Incompatibles: Oxidizers, bases, reducing agents; violent reaction with phosphorus oxychloride.

  • Decomposition: Carbon oxides under fire conditions.


Toxicology & Ecology

  • Acute Toxicity (acetone): Oral LD₅₀ rat 5800 mg/kg; Inhalation LC₅₀ rat (8 h) 50,100 mg/m³; Dermal LD₅₀ guinea pig 7426 mg/kg.

  • Effects: Eye irritation; CNS depression (drowsiness/dizziness). Not a sensitizer; not classified for carcinogenicity, mutagenicity, or reproductive toxicity.

  • Aquatic Toxicity: LC₅₀ (rainbow trout, 96 h) 5,540 mg/L; EC₅₀ (Daphnia, 48 h) 8,800 mg/L.

  • Biodegradability: Readily biodegradable (~91%).


Transport & Disposal

  • UN 1090, Acetone, Class 3, PG II (US DOT/IMDG/IATA); ERG 127.

  • Marine Pollutant: Ingredients classified by DOT as a marine pollutant (per SDS).

  • Disposal: Incinerate in approved facility; avoid release to environment; comply with federal/state/local regulations.


Regulatory Status

  • TSCA: All components listed.

  • SARA 311/312: Acute Health—Yes; Chronic—No; Fire—Yes; Reactivity—No.

  • SARA 302/304/313: Not subject to reporting.

  • Prop 65: None listed; state regs: none noted in SDS.